Policies & Costs

TGFB1 induces fetal reprogramming and enhances intestinal regeneration
Lei Chen , Xia Qiu , Abigail Dupre , Oscar Pellon-Cardenas , Xiaojiao Fan , Xiaoting Xu , Prateeksha Rout , Katherine D Walton , Joseph Burclaff , Ruolan Zhang , Wenxin Fang , Rachel Ofer , Alexandra Logerfo , Kiranmayi Vemuri , Sheila Bandyopadhyay , Jianming Wang, Gaetan Barbet, Yan Wang, Nan Gao, Ansu O Perekatt, Wenwei Hu, Scott T Magness, Jason R Spence, Michael P Verzi
PubMed Link

mTORC1 activity oscillates throughout the cell cycle promoting mitotic entry and differentially influencing autophagy induction
Jay N. Joshi, Ariel D. Lerner, Frank Scallo, Alexandra N. Grumet, Paul Matteson, James H. Millonig, Alexander J. Valvezan
BioRxiv Link

Systematic engineering of uniform, highly efficient, targeted and shielded viral-mimetic nanoparticles
Zahra Karjoo , Helen O McCarthy, Parin Patel, Faranak Salman Nouri, Arash Hatefi
PubMed Link

A Recombinant Biopolymeric Platform for Reliable Evaluation of the Activity of pH-Responsive Amphiphile Fusogenic Peptides
Nouri, Faranak S. | Wang, Xing | Dorrani, Mania | Karjoo, Zahra | Hatefi, Arash
FAO Link

Genetically engineered theranostic mesenchymal stem cells for the evaluation of the anticancer efficacy of enzyme/prodrug systems
Faranak Salman Nouri, Xing Wang, Arash Hatefi
PubMed Link

Development of a Recombinant Multifunctional Biomacromolecule for Targeted Gene Transfer to Prostate Cancer Cells
Arash Hatefi, Zahra Karjoo, Alireza Nomani
PubMed Link

Evaluation of genotoxicity and mutagenic effects of vector/DNA nanocomplexes in transfected mesenchymal stem cells by flow cytometry
Alireza Nomani, Xuguang Chen, Arash Hatefi
PubMed Link

A novel chemotherapeutic protocol for peritoneal metastasis and inhibition of relapse in drug resistant ovarian cancer
Siddik Sarkar, Obeid M Malekshah, Alireza Nomani, Niket Patel, Arash Hatefi
PubMed Link

Bioengineering a non-genotoxic vector for genetic modification of mesenchymal stem cells
Xuguang Chen, Alireza Nomani, Niket Patel, Faranak S Nouri, Arash Hatefi
PubMed Link

Bioengineered adipose-derived stem cells for targeted enzyme-prodrug therapy of ovarian cancer intraperitoneal metastasis
Obeid M Malekshah, Siddik Sarkar, Alireza Nomani, Niket Patel, Parisa Javidian, Michael Goedken, Marianne Polunas , Pedro Louro, Arash Hatefi
PubMed Link

Gadolinium-labeled affibody-XTEN recombinant vector for detection of HER2+ lesions of ovarian cancer lung metastasis using quantitative MRI
Alireza Nomani, Geng Li, Siavash Yousefi, Shawn Wu, Obeid M Malekshah, Shahryar K Nikkhoi, Mehrdad Pourfathi, Rahim Rizi, Arash Hatefi                                                             PubMed Link

Bispecific killer cell engager with high affinity and specificity toward CD16a on NK cells for cancer immunotherapy
Shahryar Khoshtinat Nikkhoi, Geng Li, Suha Eleya, Ge Yang, Venu Gopal Vandavasi, Arash Hatefi
PubMed Link

Stem cell-assisted enzyme/prodrug therapy makes drug-resistant ovarian cancer cells vulnerable to natural killer cells through upregulation of NKG2D ligands
Geng Li, Shahryar Khoshtinat Nikkhoi, Arash Hatefi
PubMed Link

A high affinity and specificity anti-HER2 single-domain antibody (VHH) that targets trastuzumab’s epitope with versatile biochemical, biological, and medical applications
Shahryar Khoshtinat Nikkhoi, Hediyeh Heydarzadeh, Venu Gopal Vandavasi, Ge Yang, Pedro Louro, Marianne Polunas, Hajar Owji, Arash Hatefi
PubMed Link

Bispecific immune cell engager enhances the anticancer activity of CD16+ NK cells and macrophages in vitro, and eliminates cancer metastasis in NK humanized NOG mice
Shahryar Khoshtinat Nikkhoi, Ge Yang, Hajar Owji, Mayara Grizotte-Lake, Rick I Cohen, Lazaro Gil Gonzalez, Mohammad Massumi, Arash Hatefi
PubMed Link

p53-independent G1 cell cycle arrest of human colon carcinoma cells HT-29 by sulforaphane is associated with induction of p21CIP1 and inhibition of expression of cyclin D1
Guoxiang Shen, Changjiang Xu, Chi Chen, Vidya Hebbar, Ah-Ng Tony Kong
PubMed Link

Quantitative Assessment of the Cell Penetrating Properties of RI-Tat-9:  Evidence for a Cell Type-Specific Barrier at the Plasma Membrane of Epithelial Cells
Xiaoping Zhang, Li Wan, Shahriar Pooyan, Yaming Su, Carol R. Gardner, Michael J. Leibowitz, Stanley Stein, Patrick J. Sinko
ACS Link

Pluronic block copolymers alter apoptotic signal transduction of doxorubicin in drug-resistant cancer cells
Tamara Minko, Elena V Batrakova, Shu Li, Yili Li, Refika I Pakunlu, Valery Yu Alakhov, Alexander V Kabanov
PubMed Link

Overexpression of extracellular matrix metalloproteinase inducer in multidrug resistant cancer cells
Jin-Ming Yang , Zude Xu, Hao Wu, Hongguang Zhu, Xiaohua Wu, William N Hait
PubMed Link

Identification and characterization of an inhibitor of eukaryotic elongation factor 2 kinase against human cancer cell lines
Sonia Arora, Jin-Ming Yang, Terri Goss Kinzy, Ryutaro Utsumi, Tadashi Okamoto, Takashi Kitayama, Pedro A Ortiz, William N Hait
PubMed Link

Translation elongation factor 1A is essential for regulation of the actin cytoskeleton and cell morphology
Stephane R Gross, Terri Goss Kinzy
PubMed Link

Novel Characteristics of the Biological Properties of the Yeast Saccharomyces cerevisiae Eukaryotic Initiation Factor 2A
Anton A. Komar, Stephane R. Gross, Diane Barth-Baus, Ryan Strachan, Jack O. Hensold, Terri Goss Kinzy, William C. Merrick
JBC Link

Mechanisms mediating the biologic activity of synthetic proline, glycine, and hydroxyproline polypeptides in human neutrophils
Barry Weinberger, Nazeeh Hanna, Jeffrey D Laskin, Diane E Heck, Carol R Gardner, Donald R Gerecke, Debra L Laskin
PubMed Link

Effects of ibuprofen and hypoxia on neutrophil apoptosis in neonates
Nazeeh Hanna, Sarah Graboski, Debra L Laskin, Barry Weinberger
PubMed Link